家庭数据揭示儿童抑郁和焦虑的两种遗传途径
一项发表在《精神健康自然》杂志上的研究分析了挪威家庭的数据，揭示了儿童易患内化问题的遗传机制。
研究发现，儿童的抑郁和焦虑倾向不仅受自身基因的影响，还受到父母基因的间接影响，可能通过父母的性格和家庭环境传递。
早期（8岁时）父母的基因影响更为显著，而随着孩子进入青春期（14岁时），自身的基因更容易发挥作用。
研究人员利用机器学习方法分析了近万个母子父亲三人组的遗传和心理健康数据，构建了遗传模型，并强调了遗传与环境相互作用的重要性。
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Razieh Chegeni, post-doctoral researcher at Promenta Research Center. Credit: Thor Broedreskift
Many common mental health disorders, including depression and anxiety, are associated with a tendency to internalize problems or, in other words, to direct feelings inwards instead of expressing them and sharing them with others. Past studies suggest that this tendency to withdraw from others and suppress emotions often emerges early, during childhood and adolescence.
Researchers at the University of Oslo and the Norwegian Institute of Public Health analyzed data collected from families in Norway to investigate the genetic underpinnings of children's susceptibility to internalize problems.
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